Pharmaceutical Mixing & Processing Equipment

Pharmaceutical Mixing & Processing Equipment

Quality in its purest form

B&P Littleford manufactures high-quality, long-lasting pharmaceutical processing equipment for wide variety of uses in the pharmaceutical industry.

B&P Littleford’s batch and continuous mixers, centrifugal extractors, and separators are expertly engineered, skillfully crafted, and rigidly tested to meet the stringent regulations for cleanliness, accuracy, and consistency required in the pharmaceutical industry. 

B&P Littleford’s pharmaceutical mixing equipment and separators provide the power and precision you need for all exacting pharmaceutical applications, including blending liquids, dispersing gums and stabilizers, and creating complex emulsions.

For more information, request a quote today!

Important part of the pharmaceutical process

Mixing, blending, and separating are critical in manufacturing pharmaceutical products. Next to the formula, how ingredients are mixed, blended and separated determines whether or not a drug will deliver the accurate dosage, have an acceptable appearance and texture, and be stable for the appropriate length of time.

Use B&P Littleford’s specialized pharmaceutical processing equipment, mixers and separators to:

  • Combine raw ingredients
  • Prepare fine emulsions
  • Reduce particle size
  • Kindle chemical reactions
  • Dissolve components
  • Facilitate heat transfers

Supplying the features you want

B&P Littleford’s pharmaceutical mixers and separators:

  • Built with FDA-approved materials
  • 3-A certified
  • Comply with strict GMP requirements
  • Compact design
  • Clear line arrangement for aseptic process management
  • Durable
  • Easy to clean
  • Easy to maintain
  • Simple to operate
  • Treat products gently
  • Efficiently recover active ingredients

Providing the product you need

B&P Littleford’s batch and continuous mixers, centrifugal extractors, and separators are ideal for manufacturing the life-sustaining and life-saving medicines and drugs for patients across the world, including:

  • Oral suspensions
  • Saline solutions
  • Antacids
  • Cough syrups
  • Nutraceuticals
  • Solid dose coatings
  • Gel caps
  • Therapeutic creams and lotions

Podbielniak® Contactor (POD®)

B&P’s Podbielniak® Contactor (POD®) is a horizontal axis liquid-liquid centrifugal extractor that processes liquids for accelerated solvent extraction. The two main functions of this machine are liquid-liquid separation and the liquid-liquid extraction process through counter-current flow. B&P’s Podbielniak® Contactor (POD®):

  • Reliable: POD® has been in service for more than 60 years
  • Runs smoothly: Uses a dual bearing lubrication system - one for normal operation, one for flush cleaning
  • Durable: Lower operating rpm means rotating parts last longer
  • Easy to clean: Rotor elements use Asco tubes and Ferralium alloy liners
  • Sturdily construction: Made of 316 stainless steel. Non-contact parts and attachments in 304 stainless steel and chrome

In the pharmaceutical industry, use the POD to process:

  • Hydrogen peroxide
  • Fish oils
  • Antibiotics
  • Penicillin
  • Tylosin
  • Bacitracin
  • Erthromycin
  • Alkaloids
  • Estrogen
  • Lysergic/DCETH
  • Nicotinic acid
  • Phytochemicals
  • Vitamin A
  • Vitamin C
  • Statins
  • Vaccines
  • Anti-cancer drugs
  • Steroids
  • Enzymes
  • Hormones

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Pusher Centrifuge

B&P Littleford's Pusher Centrifuges (liquid-solid separation centrifuges) relentlessly separate coarse solids from free-draining crystalline slurries in the most extreme conditions. The impressive reliability record for Pusher Centrifuges is grounded in its sound design, precise engineering, and top-grade construction.

Pusher Centrifuges are developed and manufactured for standard products, but can be customized for special or difficult solid separation applications.

B&P Littleford Pusher Centrifuges feature:

  • Single-piece reversible wedge-slot screen that efficiently separates solids and liquids
  • Screen supported by a centrifugally cast, milled-slot cage basket
  • Heavy-duty bearings carry the main hollow shaft, which drives the basket
  • Belt-driven hydraulic pump for energy efficiency, safety and reliability
  • Internal, self-contained hydraulic piston driving the pusher shaft
  • Rugged base provides rigid support for the entire rotating assembly
  • Cooling coils that maintain the hydraulic system temperature at optimum levels

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Horizontal Plow Mixer

B&P Littleford Horizontal Plow Mixer creates fluid mixing action. The mixing tools project and hurl material away from a wall into free space in a crisscross direction, and inversely back again. The plow separates and lifts the product in a three-dimensional motion, while the number and arrangement of the tools insure agitation back and forth along the length of the vessel.

The size, number, geometric shape, arrangement, and peripheral speed of the mixing tools are designed to achieve this mixing action for each specific application. When required, the mix action is assisted by high shear chopper devices: independent high-speed motors with customized blades for adding shear to the product mix.

The Horizontal Plow Mixer also features:

  • Large doors allow full interior access
  • CIP/SIP hardware options available
  • "Easy Clean" design available for batch or continuous material mixing
  • Split seal assembly
  • No special cleaning or maintenance tools required
  • Bearings and drive components not disturbed during cleaning

In the pharmaceutical industry, use the Horizontal Plow Mixer to process:

  • Dental Paste
  • API
  • Nutraceutical
  • Enzymes
  • Riboflavin
  • Ginseng

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Double Arm/Sigma Blade Mixer

The Double Arm/Sigma Blade Mixer is simple to operate, easy to clean, can be used to mix:

For the pharmaceutical industry, the Double Arm/Sigma Blade Mixer includes a wide range of features that can be customized to meet your exacting carbon paste mixing specifications:

  • Available in laboratory sizes and production sizes up to 900 gallons
  • Sturdy stainless steel construction with required polish
  • Spray injection
  • E-Z clean shaft seals
  • Direct shaft mount drives
  • Variable speed motors
  • Computerized controls
  • ASME jackets for cooling and heating
  • Cored agitators for enhanced product temperature control
  • Tilt or valve discharge
  • Full vacuum operation
  • Vacuum equipped packing glands

 Delivering the service you deserve

B&P Littleford designs, develops and delivers a wide range of mixing, drying, compounding, reacting, extracting and centrifugal separation equipment for many different manufacturing applications.

  • More than 100 years of industry experience
  • Quality parts and service
  • Professional, knowledgeable staff
  • Top-notch testing facilities

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Pharmaceuticals Applications & Equipment

Application Equipment
Hydrogen Peroxide POD
Fish Oils POD
Antbiotics POD
Penicillin POD
Tylosin POD
Bacitracin POD
Erthromycin POD
Alkaloids POD
Estrogen POD
Lysergic/DCETH POD
Nicotinic Acid POD
Phytochemicals POD
Vitamin A POD
Vitamin C POD
Statins POD
Vaccine Production POD
Anti-cancer drugs POD
Steroids POD
Enzymes POD
Hormones POD
Lysine Pusher
Pharmaceuticals Double Arm
Dental Paste Plow Mixer
API Plow Mixer
Nutraceutical Plow Mixer
Enzymes Plow Mixer
Riboflavin Plow Mixer
Ginseng Plow Mixer


Partial application list. Please contact us to discuss your application in more detail.